STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIAS3Protein inhibitor of activated STAT 3. (626 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription.
   
 0.960
STAT1
Signal transducer and activator of transcription.
   
 0.888
STAT5B
Signal transducer and activator of transcription.
   
 0.840
STAT5A
Signal transducer and activator of transcription.
   
 0.840
STAT4
Signal transducer and activator of transcription.
   
 0.827
STAT6
Signal transducer and activator of transcription.
   
 0.821
UBE2I
Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.802
SUMO1
Small ubiquitin-related modifier.
    
 0.769
G3UN99_LOXAF
Small ubiquitin-related modifier.
    
 0.769
KCTD2
Potassium channel tetramerization domain containing 2.
    
 0.752
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.