Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SWAP70Switching B cell complex subunit SWAP70. (585 aa)    
Predicted Functional Partners:
BRCC3
BRCA1/BRCA2-containing complex subunit 3.
    
   0.780
BABAM1
Uncharacterized protein.
    
   0.776
BABAM2
BRISC and BRCA1 A complex member 2.
    
  0.775
ABRAXAS2
Abraxas 2, BRISC complex subunit.
    
   0.606
CAPS2
Calcyphosine 2.
     
 0.493
TMEM19
Transmembrane protein 19.
      
 0.492
POLM
DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.
      
 0.492
G3T8V5_LOXAF
Anoctamin.
      
 0.491
BRK1
BRICK1 subunit of SCAR/WAVE actin nucleating complex.
     
 0.480
LYN
Tyrosine-protein kinase.
   
 0.450
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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