STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ESPL1Extra spindle pole bodies like 1, separase. (2085 aa)    
Predicted Functional Partners:
PTTG1
Uncharacterized protein.
   
 0.998
RAD21
RAD21 cohesin complex component.
   
 0.981
REC8
REC8 meiotic recombination protein.
   
 0.976
PLK1
Serine/threonine-protein kinase PLK.
   
 0.972
SMC3
Structural maintenance of chromosomes protein.
   
 0.970
BUB1B
Uncharacterized protein.
   
 
 0.969
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.968
RAD21L1
RAD21 cohesin complex component like 1.
   
 0.963
SMC1B
Structural maintenance of chromosomes protein.
   
 0.961
SMC1A
Structural maintenance of chromosomes protein.
   
 0.961
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.