STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (819 aa)    
Predicted Functional Partners:
USP16
Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
     
  0.870
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
    
 0.728
OTUB1
Ubiquitin thioesterase.
      
 0.620
UBB
Ubiquitin B.
    
 0.567
UBC
Uncharacterized protein.
    
 0.567
ICE2
Interactor of little elongation complex ELL subunit 2.
      
 0.565
FAXC
Failed axon connections homolog, metaxin like GST domain containing.
      
 0.560
G3T7Q2_LOXAF
Uncharacterized protein.
      
 0.546
COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
      
 0.545
KLHL7
Kelch like family member 7.
      
 0.545
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.