Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM91A1Family with sequence similarity 91 member A1. (836 aa)    
Predicted Functional Partners:
C17orf75
Chromosome 17 open reading frame 75.
    
 
 0.985
WDR11
WD repeat domain 11.
   
 0.947
TBC1D23
TBC1 domain family member 23.
   
 
 0.911
NUDCD1
NudC domain containing 1.
    
 
 0.779
G3U3Z9_LOXAF
Uncharacterized protein.
      
 0.751
RHOH
Ras homolog family member H.
     
  0.727
G3SNX5_LOXAF
Uncharacterized protein.
      
 0.721
MIER1
MIER1 transcriptional regulator.
      
 0.654
CLUH
Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family.
      
 0.643
GSKIP
GSK3B interacting protein.
      
 0.641
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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