Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CATSPER3Cation channel sperm associated 3. (375 aa)    
Predicted Functional Partners:
CATSPER2
Cation channel sperm associated 2.
  
 
0.985
CATSPERB
Cation channel sperm associated auxiliary subunit beta.
    
 0.970
CATSPERD
Cation channel sperm associated auxiliary subunit delta.
    
 0.967
CATSPER4
Cation channel sperm associated 4.
  
0.966
EFCAB9
EF-hand calcium binding domain 9.
  
 
 0.962
G3UIJ0_LOXAF
Ion_trans domain-containing protein.
  
0.956
G3SUK6_LOXAF
Uncharacterized protein.
    
 0.908
CATSPERE
Catsper channel auxiliary subunit epsilon.
    
 0.907
CATSPERZ
Catsper channel auxiliary subunit zeta.
    
 0.876
CACNA1I
Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]
   
0.807
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (18%) [HD]