STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CALHM2Calcium homeostasis modulator family member 2. (323 aa)    
Predicted Functional Partners:
UGT3A2
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
    0.629
G3TLL1_LOXAF
Uncharacterized protein.
   
    0.629
C1orf109
Chromosome 1 open reading frame 109.
   
    0.625
SLCO1A2
Solute carrier organic anion transporter family member.
   
    0.621
LIX1
Limb and CNS expressed 1.
   
    0.612
RUBCNL
Rubicon like autophagy enhancer.
   
    0.608
CWC25
CWC25 spliceosome associated protein homolog.
   
    0.604
PGM2
Phosphoglucomutase 2.
   
  
 0.579
MOCS3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
    0.570
ACOT11
Acyl-CoA thioesterase 11.
   
    0.509
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (30%) [HD]