STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSC1TSC complex subunit 1. (869 aa)    
Predicted Functional Partners:
TSC2
TSC complex subunit 2.
   
 0.999
TBC1D7
TBC1 domain family member 7.
    
 0.996
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
   
 0.964
RHEB
Ras homolog, mTORC1 binding.
   
 0.952
RHEBL1
RHEB like 1.
   
 0.952
RPS6KA1
Non-specific serine/threonine protein kinase.
    
 0.937
RPS6KA2
Ribosomal protein S6 kinase.
    
 0.928
RPS6KA3
Ribosomal protein S6 kinase.
    
 0.926
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.924
PRKAA2
Non-specific serine/threonine protein kinase.
    
 0.921
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.