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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSC1TSC complex subunit 1. (869 aa)    
Predicted Functional Partners:
TSC2
TSC complex subunit 2.
   
 0.999
TBC1D7
TBC1 domain family member 7.
    
 0.999
RHEB
Ras homolog, mTORC1 binding.
  
 0.981
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.972
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.972
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.953
PRKAA2
Non-specific serine/threonine protein kinase.
    
 0.953
PRKAA1
Non-specific serine/threonine protein kinase.
    
 0.953
PRKAG1
Protein kinase AMP-activated non-catalytic subunit gamma 1.
   
 0.950
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
     
 0.950
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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