Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TACC1Transforming acidic coiled-coil containing protein 1. (817 aa)    
Predicted Functional Partners:
CKAP5
Cytoskeleton associated protein 5.
    
 0.901
G3U7T5_LOXAF
TACC_C domain-containing protein.
    
 
 0.831
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.796
PLXNB2
Sema domain-containing protein.
    
  0.791
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
   0.786
VAPA
VAMP associated protein A.
    
  0.730
NIF3L1
NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
    
   0.702
CCDC125
Coiled-coil domain containing 125.
      
 0.661
LSM7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.
   
 
 0.648
CEP120
Centrosomal protein 120.
    
 0.605
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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