Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTP4A2Protein tyrosine phosphatase 4A2. (168 aa)    
Predicted Functional Partners:
RABGGTB
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 0.922
AUP1
AUP1 lipid droplet regulating VLDL assembly factor.
    
 
 0.672
CNNM1
Cyclin and CBS domain divalent metal cation transport mediator 1.
    
 
 0.628
ACTG2
Actin gamma 2, smooth muscle.
   
 
 0.493
RABGGTA
Rab geranylgeranyltransferase subunit alpha.
     
  0.487
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
     
  0.486
ATP5F1C
ATP synthase subunit gamma.
      
 0.484
CNNM3
Cyclin and CBS domain divalent metal cation transport mediator 3.
    
 
 0.469
CNNM4
Cyclin and CBS domain divalent metal cation transport mediator 4.
    
 
 0.469
CNNM2
Cyclin and CBS domain divalent metal cation transport mediator 2.
    
 
 0.469
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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