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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IBTKInhibitor of Bruton tyrosine kinase. (1353 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.736
ANKRD9
Ankyrin repeat domain 9.
   
 0.726
DNAJC17
DnaJ heat shock protein family (Hsp40) member C17.
      
 0.717
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.703
WDYHV1
WDYHV motif containing 1.
      
 0.666
BTK
Tyrosine-protein kinase.
   
 0.643
CACUL1
CDK2 associated cullin domain 1; Belongs to the cullin family.
   
 0.625
ABTB1
Ankyrin repeat and BTB domain containing 1.
   
 0.549
APBA3
Amyloid beta precursor protein binding family A member 3.
      
 0.536
IRAK1BP1
Interleukin 1 receptor associated kinase 1 binding protein 1.
    
 
 0.532
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.