Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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Experiments
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[Homology]
Score
PGRMC2Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (223 aa)    
Predicted Functional Partners:
PGRMC1
Uncharacterized protein.
   
 0.897
TMEM97
Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
    
 0.890
PM20D2
Peptidase M20 domain-containing protein 2; Belongs to the peptidase M20A family.
      
 0.738
G3TQ14_LOXAF
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
   
 
 0.724
PGR
NR LBD domain-containing protein.
    
 
 0.689
TENT2
Terminal nucleotidyltransferase 2.
     
 0.652
PAQR8
Progestin and adipoQ receptor family member 8.
   
 
 0.602
PAQR7
Progestin and adipoQ receptor family member 7.
   
 
 0.602
RHOG
Ras homolog family member G.
    
  0.586
PAQR5
Progestin and adipoQ receptor family member 5.
   
 
 0.572
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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