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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGRMC2Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (223 aa)    
Predicted Functional Partners:
PGR
NR LBD domain-containing protein.
    
 
 0.650
PM20D2
Peptidase M20 domain-containing protein 2; Belongs to the peptidase M20A family.
     
 0.583
ATAD3A
ATPase family AAA domain containing 3A.
      
 0.522
GPER1
G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.504
RHOG
Ras homolog family member G.
    
 0.480
TMEM214
Transmembrane protein 214.
      
 0.439
BCAP29
B cell receptor associated protein 29.
   
 0.432
BCAP31
B cell receptor associated protein 31.
   
 0.432
FDX1
Uncharacterized protein.
   
  
 0.423
CYB5B
Cytochrome b5 type B; Belongs to the cytochrome b5 family.
   
  
 0.406
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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