Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NANOS3Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (180 aa)    
Predicted Functional Partners:
DAZL
RRM domain-containing protein.
    
 
 0.811
DND1
DND microRNA-mediated repression inhibitor 1.
    
 
 0.778
PIWIL1
Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.
   
 
 0.743
TFAP2C
Transcription factor AP-2 gamma.
   
 0.674
ZBTB16
Zinc finger and BTB domain containing 16.
    
 
 0.633
PUM2
Pumilio RNA binding family member 2.
   
 
 0.631
ATAT1
Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...]
      
 0.623
G3U9L9_LOXAF
Uncharacterized protein.
      
 0.622
LIN28A
Lin-28 homolog A.
   
  
 0.620
PRDM1
PR/SET domain 1.
     
 0.608
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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