Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (392 aa)    
Predicted Functional Partners:
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.995
PDHX
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.994
DLD
Dihydrolipoyl dehydrogenase.
 
 
 0.993
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
 
 0.984
PDK1
Protein-serine/threonine kinase.
   
 0.965
PDK3
Protein-serine/threonine kinase.
   
 0.956
PDK2
Protein-serine/threonine kinase.
   
 0.928
GPI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.907
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
   
 0.897
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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