Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRDX2Peroxiredoxin 2. (112 aa)    
Predicted Functional Partners:
SRXN1
Sulfiredoxin 1.
   
 0.923
PRDX5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.862
TXN
Thioredoxin.
  
 0.836
TXNDC2
Thioredoxin; Belongs to the thioredoxin family.
  
 0.836
NME8
NME/NM23 family member 8.
  
 0.757
TXN2
Thioredoxin 2.
  
 0.751
PRDX4
Peroxiredoxin 4.
   
   0.750
TXNDC8
Thioredoxin domain containing 8.
  
 0.738
SESN2
Sestrin 2.
    
 0.665
LTC4S
Leukotriene C4 synthase.
   
 
 0.653
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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