Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MLYCDMalonyl-CoA decarboxylase. (497 aa)    
Predicted Functional Partners:
ACSF3
Acyl-CoA synthetase family member 3.
   
 0.946
FASN
Fatty acid synthase.
     
 0.907
ACSS1
Acetyl-coenzyme A synthetase.
     
 0.906
MCAT
Malonyl-CoA-acyl carrier protein transacylase.
  
 
 0.900
ACSS2
Acyl-CoA synthetase short chain family member 2.
     
 0.894
ACAT1
Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.890
ACAT2
Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.887
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.885
ALDH6A1
Aldehyde dehydrogenase 6 family member A1.
   
 
 0.881
PRKAA2
Non-specific serine/threonine protein kinase.
     
 0.874
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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