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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1061 aa)    
Predicted Functional Partners:
BUB3
BUB3 mitotic checkpoint protein.
   
 0.998
BUB1B
Uncharacterized protein.
   
0.995
MAD1L1
Mitotic arrest deficient 1 like 1.
  
 
 0.994
NDC80
NDC80 kinetochore complex component.
   
 0.985
LOC100668722
HORMA domain-containing protein.
   
 0.982
LOC100667589
HORMA domain-containing protein.
   
 0.982
TTK
TTK protein kinase.
   
 
 0.979
CDC20B
Cell division cycle 20B.
   
 0.973
CDC20
Cell division cycle 20.
   
 0.973
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.971
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.