STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HBEGFHeparin binding EGF like growth factor. (208 aa)    
Predicted Functional Partners:
EGFR
Receptor protein-tyrosine kinase.
    
 0.997
ADAM17
ADAM metallopeptidase domain 17.
    
 0.948
MMP9
Matrix metallopeptidase 9.
   
 0.904
MMP14
Matrix metallopeptidase 14.
   
 0.894
MMP16
Matrix metallopeptidase 16.
   
 0.888
MMP24
Matrix metallopeptidase 24.
   
 0.886
MMP15
Matrix metallopeptidase 15.
   
 0.885
S1PR3
Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family.
     
 0.872
ERBB4
GF_recep_IV domain-containing protein.
    
 0.865
ADAM10
ADAM metallopeptidase domain 10.
    
 0.863
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.