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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEF1AKNMTEEF1A lysine and N-terminal methyltransferase. (696 aa)    
Predicted Functional Partners:
TMED5
Transmembrane p24 trafficking protein 5.
      
 0.741
TM9SF4
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
      
 0.678
PLAGL2
PLAG1 like zinc finger 2.
      
 0.665
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.657
EEF1AKMT2
EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
      
 0.585
PLPP6
Phospholipid phosphatase 6.
      
 0.574
ALKBH3
AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase.
     
 0.571
METTL14
Methyltransferase like 14; Belongs to the MT-A70-like family.
      
 0.562
HCK
Tyrosine-protein kinase.
    
 
 0.558
TRMT44
tRNA methyltransferase 44 homolog.
   
  
 0.545
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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