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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMPDL3BAcid sphingomyelinase-like phosphodiesterase. (456 aa)    
Predicted Functional Partners:
CACHD1
Cache domain containing 1.
      
 0.645
SMPD2
Sphingomyelin phosphodiesterase 2.
      
 0.587
XKR8
XK-related protein.
 
    
 0.551
EMC1
ER membrane protein complex subunit 1.
   
  
 0.545
CERK
Ceramide kinase.
    
 
 0.538
GGCX
Gamma-glutamyl carboxylase.
      
 0.536
PRUNE1
Prune exopolyphosphatase 1.
    
 
 0.529
THEMIS2
Thymocyte selection associated family member 2.
      
 0.526
STT3A
STT3 oligosaccharyltransferase complex catalytic subunit A.
      
 0.524
ASAH2
Neutral ceramidase.
      
 0.524
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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