STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZFYVE9Zinc finger FYVE domain-containing protein. (1397 aa)    
Predicted Functional Partners:
SMAD2
Mothers against decapentaplegic homolog.
   
 0.951
SMAD3
SMAD family member 3.
   
 0.951
TGFBR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
 0.885
ZFYVE16
Zinc finger FYVE domain-containing protein.
    
  0.871
PML
Promyelocytic leukemia.
    
 
 0.806
PTPN23
Protein tyrosine phosphatase non-receptor type 23.
   
 
 0.782
SMAD4
Mothers against decapentaplegic homolog.
   
 0.769
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.708
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.708
SMAD9
Mothers against decapentaplegic homolog.
   
 0.655
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.