STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EGR4Early growth response 4. (479 aa)    
Predicted Functional Partners:
NAB1
NGFI-A binding protein 1.
    
 0.686
NAB2
NGFI-A binding protein 2.
   
 0.685
MAPK7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.609
NPAS4
Neuronal PAS domain protein 4.
   
 
 0.573
MSL3
MSL complex subunit 3.
    
 0.521
BEX3
Brain expressed X-linked 3.
      
 0.478
EGR2
Early growth response 2.
   
 0.466
NR4A1
Nuclear receptor subfamily 4 group A member 1.
   
 
 0.463
ADGRG6
Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family.
      
 0.438
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit.
   
 0.434
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.