Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIAA0586KIAA0586. (1361 aa)    
Predicted Functional Partners:
DACT1
Dishevelled binding antagonist of beta catenin 1.
      
 0.737
CEP120
Centrosomal protein 120.
    
 0.625
CEP290
Centrosomal protein 290.
    
 0.602
WDR35
WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking.
      
 0.554
CEP97
Centrosomal protein 97.
   
 
 0.549
OFD1
OFD1 centriole and centriolar satellite protein.
   
 0.547
IFT88
Intraflagellar transport 88.
    
 0.535
IQCE
IQ motif containing E.
    
 0.520
DYNC2H1
Dynein cytoplasmic 2 heavy chain 1.
    
 0.515
IFT80
Intraflagellar transport 80.
    
 0.505
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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