Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM69Transmembrane protein 69. (213 aa)    
Predicted Functional Partners:
TXNDC12
Thioredoxin domain containing 12.
      
 0.663
METAP1
Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
   
  
 0.642
IPO9
Importin 9.
      
 0.568
AKR7L
Aldo-keto reductase family 7 like (gene/pseudogene).
      
 0.505
CCDC137
Coiled-coil domain containing 137.
      
 0.503
SPICE1
Uncharacterized protein.
      
 0.500
KLHL41
Kelch like family member 41.
      
 0.500
DYNLT1
Dynein light chain Tctex-type 1.
      
 0.497
HGSNAT
Heparan-alpha-glucosaminide N-acetyltransferase.
      
 0.482
LIMCH1
LIM and calponin homology domains 1.
      
 0.419
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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