STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRCH2Leucine rich repeats and calponin homology domain containing 2. (765 aa)    
Predicted Functional Partners:
DOCK8
Dedicator of cytokinesis 8; Belongs to the DOCK family.
   
 
 0.823
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
    
   0.729
ARPC3
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
   0.720
MOB1B
MOB kinase activator 1B.
    
 
 0.634
AMOT
Angiomotin.
    
 0.513
HTR2C
5-hydroxytryptamine receptor 2C.
      
 0.502
DOCK7
Dedicator of cytokinesis 7; Belongs to the DOCK family.
   
 
 0.496
DOCK6
Dedicator of cytokinesis 6; Belongs to the DOCK family.
   
 
 0.496
TTC32
Tetratricopeptide repeat domain 32.
    
 0.443
DARS2
Aspartyl-tRNA synthetase 2, mitochondrial.
      
 0.419
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.