STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRK1Leucine rich repeat kinase 1. (2015 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.843
BAG5
BCL2 associated athanogene 5.
    
   0.778
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
 0.659
RTL4
Retrotransposon Gag like 4.
    
 0.638
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
   
 0.614
EGFR
Receptor protein-tyrosine kinase.
    
 0.611
SHC1
SHC adaptor protein 1.
    
  0.594
SHC3
SHC adaptor protein 3.
    
  0.594
BAG1
BCL2 associated athanogene 1.
  
 
   0.562
VGLL4
Vestigial like family member 4.
    
 
 0.548
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.