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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (394 aa)    
Predicted Functional Partners:
CERK
Ceramide kinase.
    
 0.960
GBA2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
    
 0.960
SMPD1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
   
 0.959
GALC
Galactosylceramidase.
     
 0.955
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.955
CERS2
Ceramide synthase 2.
    
 0.955
ASAH2
Neutral ceramidase.
     
 0.950
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.946
SPHK2
Sphingosine kinase 2.
    
 0.946
SPHK1
Sphingosine kinase 1.
    
 0.946
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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