STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD70TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (198 aa)    
Predicted Functional Partners:
CD27
CD27 molecule.
    
 0.979
TNFRSF4
TNF receptor superfamily member 4.
   
  
 0.740
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
      
 0.735
TNFRSF9
TNF receptor superfamily member 9.
      
 0.711
CD40
CD40 molecule.
   
  
 0.656
TNFSF9
TNF superfamily member 9; Belongs to the tumor necrosis factor family.
   
  
 0.597
ICOS
Inducible T cell costimulator.
      
 0.544
G3T1U1_LOXAF
TNFR-Cys domain-containing protein.
   
  
 0.539
CD1C
CD1c molecule.
   
  
 0.521
G3U4G1_LOXAF
Ig-like domain-containing protein.
      
 0.487
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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