Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMIGD1Transmembrane and immunoglobulin domain containing 1. (261 aa)    
Predicted Functional Partners:
GUCA2A
Guanylate cyclase activator 2A.
   
  
 0.926
OTOP3
Otopetrin 3.
      
 0.594
CLRN3
Clarin 3.
   
  
 0.565
BLMH
Bleomycin hydrolase; Belongs to the peptidase C1 family.
 
      0.548
MRM3
Mitochondrial rRNA methyltransferase 3.
      
 0.546
GUCA2B
Guanylate cyclase activator 2B.
   
  
 0.493
TMEM86B
Transmembrane protein 86B.
      
 0.455
AMN
Amnion associated transmembrane protein.
   
  
 0.446
SLC10A2
Solute carrier family 10 member 2.
   
  
 0.433
SLC10A6
Solute carrier family 10 member 6.
   
  
 0.433
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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