Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SLC4A2Anion exchange protein. (1235 aa)    
Predicted Functional Partners:
SLC26A7
Anion exchange transporter.
     
 0.914
SLC12A2
Solute carrier family 12 member 2.
   
 
 0.665
VDAC2
Voltage dependent anion channel 2.
      
 0.634
SLC9A4
Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
    
 
 0.625
G3UH94_LOXAF
STAS domain-containing protein.
     
 0.606
SLC26A11
Solute carrier family 26 member 11.
     
 0.604
CD109
CD109 molecule.
      
 0.570
SLC12A1
Solute carrier family 12 member 1.
   
 
 0.545
CA2
Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family.
   
 
 0.544
CA11
Carbonic anhydrase 11; Belongs to the alpha-carbonic anhydrase family.
   
 
 0.537
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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