STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC14A1Urea transporter; Belongs to the urea transporter family. (440 aa)    
Predicted Functional Partners:
AQP4
Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.568
AQP2
Aquaporin 2; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.546
PPARGC1A
PPARG coactivator 1 alpha.
      
 0.545
AQP8
Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.526
ACE
Angiotensin-converting enzyme.
      
 0.514
AGT
Angiotensinogen; Belongs to the serpin family.
      
 0.455
G3SS82_LOXAF
Uncharacterized protein.
      
 0.450
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
      
 0.447
GSK3A
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
      
 0.447
ECM2
Extracellular matrix protein 2.
      
 0.441
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.