node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDH18A1 | BCKDHA | ENSLAFP00000013424 | ENSLAFP00000024775 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.725 |
ALDH18A1 | ENO2 | ENSLAFP00000013424 | ENSLAFP00000004703 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Enolase 2. | 0.439 |
ALDH18A1 | GPI | ENSLAFP00000013424 | ENSLAFP00000011528 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.758 |
ALDH18A1 | H6PD | ENSLAFP00000013424 | ENSLAFP00000014863 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. | 0.725 |
ALDH18A1 | MYCBPAP | ENSLAFP00000013424 | ENSLAFP00000021404 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | MYCBP associated protein. | 0.775 |
ALDH18A1 | PGK1 | ENSLAFP00000013424 | ENSLAFP00000009988 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Phosphoglycerate kinase. | 0.775 |
ALDH18A1 | PGK2 | ENSLAFP00000013424 | ENSLAFP00000007176 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Phosphoglycerate kinase. | 0.775 |
ALDH18A1 | PNMA8B | ENSLAFP00000013424 | ENSLAFP00000007782 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Uncharacterized protein. | 0.754 |
ALDH18A1 | TALDO1 | ENSLAFP00000013424 | ENSLAFP00000004642 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.792 |
ALDH18A1 | TPI1 | ENSLAFP00000013424 | ENSLAFP00000018313 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Triosephosphate isomerase. | 0.764 |
BCKDHA | ALDH18A1 | ENSLAFP00000024775 | ENSLAFP00000013424 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.725 |
BCKDHA | ENO2 | ENSLAFP00000024775 | ENSLAFP00000004703 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Enolase 2. | 0.437 |
BCKDHA | GPI | ENSLAFP00000024775 | ENSLAFP00000011528 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.948 |
BCKDHA | H6PD | ENSLAFP00000024775 | ENSLAFP00000014863 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. | 0.725 |
BCKDHA | PNMA8B | ENSLAFP00000024775 | ENSLAFP00000007782 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Uncharacterized protein. | 0.653 |
BCKDHA | TALDO1 | ENSLAFP00000024775 | ENSLAFP00000004642 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.920 |
BCKDHA | TPI1 | ENSLAFP00000024775 | ENSLAFP00000018313 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Triosephosphate isomerase. | 0.730 |
ENO2 | ALDH18A1 | ENSLAFP00000004703 | ENSLAFP00000013424 | Enolase 2. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.439 |
ENO2 | BCKDHA | ENSLAFP00000004703 | ENSLAFP00000024775 | Enolase 2. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.437 |
ENO2 | GPI | ENSLAFP00000004703 | ENSLAFP00000011528 | Enolase 2. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.968 |