STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNAI2Snail family transcriptional repressor 2. (268 aa)    
Predicted Functional Partners:
KDM1A
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.770
RCOR1
REST corepressor 1.
    
 0.574
NRG4
Neuregulin 4.
      
 0.539
HOXB2
Homeobox B2.
   
 
 0.531
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 
 0.525
CIZ1
CDKN1A interacting zinc finger protein 1.
      
 0.517
CTNNB1
Catenin beta 1.
      
 0.517
TWIST2
Twist family bHLH transcription factor 2.
   
  
 0.514
KPNB1
Karyopherin subunit beta 1.
    
   0.499
SMAD4
Mothers against decapentaplegic homolog.
   
 
 0.474
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.