STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKL5Cyclin dependent kinase like 5. (905 aa)    
Predicted Functional Partners:
MECP2
Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
    
 
 0.764
PDZD4
PDZ domain containing 4.
      
 0.580
FMR1
Fragile X mental retardation 1.
    
 
 0.576
KCNQ2
Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.
   
  
 0.545
PCDH19
Protocadherin 19.
      
 0.525
FOXG1
Uncharacterized protein.
      
 0.522
DLG5
Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.
      
 0.517
RASSF7
Ras association domain family member 7.
      
 0.515
STXBP1
Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.513
FERMT2
Fermitin family member 2.
      
 0.510
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.