STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPCSPhosphopantothenoylcysteine synthetase. (311 aa)    
Predicted Functional Partners:
PPCDC
Phosphopantothenoylcysteine decarboxylase.
    
 0.982
COASY
Coenzyme A synthase.
  
 0.958
PANK2
Pantothenate kinase 2.
     
 0.948
PANK1
Pantothenate kinase 1.
     
 0.948
PANK3
Pantothenate kinase 3.
     
 0.948
PANK4
4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway.
     
 0.891
KYAT3
Kynurenine aminotransferase 3.
  
  0.822
KYAT1
Aminotran_1_2 domain-containing protein.
  
  0.822
CTH
Cystathionine gamma-lyase.
   
 
 0.806
GOT2
Aspartate aminotransferase.
    
  0.800
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.