STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP7Caspase 7; Belongs to the peptidase C14A family. (265 aa)    
Predicted Functional Partners:
XIAP
X-linked inhibitor of apoptosis.
   
 0.999
BIRC2
Baculoviral IAP repeat containing 2.
   
 0.965
BIRC3
Baculoviral IAP repeat containing 3.
   
 0.965
CASP3
Caspase 3; Belongs to the peptidase C14A family.
  
 
0.965
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 0.962
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
0.960
CASP8
Caspase 8; Belongs to the peptidase C14A family.
   
0.948
BIRC5
Baculoviral IAP repeat containing 5.
   
 0.947
G3ULI4_LOXAF
Uncharacterized protein; Belongs to the peptidase C14A family.
  
0.947
PARP2
Poly [ADP-ribose] polymerase.
    
 0.929
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.