STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CGASCyclic GMP-AMP synthase. (462 aa)    
Predicted Functional Partners:
DDX41
DEAD-box helicase 41.
      
 0.752
IRF3
IRF tryptophan pentad repeat domain-containing protein.
      
 0.657
STING1
Transmembrane protein 173.
    
 0.617
MNDA
Myeloid cell nuclear differentiation antigen.
    
 
 0.604
TBK1
TANK binding kinase 1.
      
 0.577
ANKRD17
Ankyrin repeat domain 17.
      
 0.574
SIRT6
Sirtuin 6.
      
 0.532
DDX58
DExD/H-box helicase 58.
      
 0.526
IRF7
Interferon regulatory factor 7.
      
 0.524
IFIH1
Interferon induced with helicase C domain 1.
      
 0.522
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.