STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLGDNA polymerase gamma, catalytic subunit. (1241 aa)    
Predicted Functional Partners:
POLG2
DNA polymerase gamma 2, accessory subunit.
   
 0.975
SSBP1
Single stranded DNA binding protein 1.
   
 
 0.755
GARS1
Glycyl-tRNA synthetase.
   
 
 0.749
TWNK
Twinkle mtDNA helicase.
   
  
 0.735
TFAM
Transcription factor A, mitochondrial.
   
 
 0.732
PRIM1
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 
 0.726
POLRMT
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
  
 0.720
DNA2
DNA replication helicase/nuclease 2.
   
 
 0.708
FANCM
FA complementation group M.
   
 
 0.632
TPI1
Triosephosphate isomerase.
    
 0.625
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.