STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHLPP1PH domain and leucine rich repeat protein phosphatase 1. (1054 aa)    
Predicted Functional Partners:
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
 
  
 0.958
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
 
  
 0.958
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2.
  
 
0.946
FKBP5
Peptidylprolyl isomerase.
    
 
 0.787
FKBP4
Peptidylprolyl isomerase.
    
 
 0.753
SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
    
 
 0.728
CAP1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.724
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.724
USP1
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 
 0.608
WDR48
WD repeat domain 48.
    
 
 0.606
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.