STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF40E3 ubiquitin protein ligase; Belongs to the BRE1 family. (1001 aa)    
Predicted Functional Partners:
RNF20
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
  
0.985
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.977
UBE2A
Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.899
UBE2B
Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.899
WAC
WW domain containing adaptor with coiled-coil.
   
 0.793
UBE2U
Ubiquitin conjugating enzyme E2 U.
   
 0.767
CDC73
Cell division cycle 73.
   
 0.760
TRIP12
Thyroid hormone receptor interactor 12.
   
  
 0.745
PAF1
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 0.731
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.712
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.