STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLLT10MLLT10 histone lysine methyltransferase DOT1L cofactor. (1071 aa)    
Predicted Functional Partners:
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 
 0.957
MLLT6
MLLT6, PHD finger containing.
    
 
0.734
PICALM
Phosphatidylinositol binding clathrin assembly protein.
      
 0.661
IZUMO4
IZUMO family member 4.
    
 
 0.588
ELL
Elongation factor for RNA polymerase II.
      
 0.530
TRIP12
Thyroid hormone receptor interactor 12.
      
 0.525
AFDN
Afadin, adherens junction formation factor.
      
 0.520
G3TFX2_LOXAF
Uncharacterized protein.
    
 
 0.488
AFF1
Uncharacterized protein.
    
 
 0.488
YEATS4
YEATS domain containing 4.
    
 
 0.482
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.