STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF11Tumor necrosis factor ligand 6B; Belongs to the tumor necrosis factor family. (319 aa)    
Predicted Functional Partners:
TNFRSF11B
Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
   
 0.998
TNFRSF11A
TNF receptor superfamily member 11a.
    
 0.998
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 
 0.787
TNFSF13B
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
   
 0.737
CD40
CD40 molecule.
   
 0.733
CSF1R
Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
  
 0.724
TNFRSF14
Uncharacterized protein.
   
 0.700
LTBR
Lymphotoxin beta receptor.
   
 0.696
TNFRSF18
Uncharacterized protein.
   
 0.691
ACP5
Tartrate-resistant acid phosphatase type 5.
      
 0.639
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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