STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGF2Insulin like growth factor 2. (175 aa)    
Predicted Functional Partners:
IGF1R
Tyrosine-protein kinase receptor.
    
 0.998
IGF2R
Insulin like growth factor 2 receptor.
    
 
 0.978
INSR
Tyrosine-protein kinase receptor.
    
 0.954
GPC3
Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
   
 
 0.952
IGFBP3
Insulin like growth factor binding protein 3.
   
 0.910
IGFBP2
Insulin like growth factor binding protein 2.
   
 0.904
G3U9C7_LOXAF
Uncharacterized protein.
   
 0.888
IGFBP6
Insulin like growth factor binding protein 6.
   
 0.873
IGFBP5
Insulin like growth factor binding protein 5.
   
 0.856
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
    
 
 0.816
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.