STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYOCDMyocardin. (937 aa)    
Predicted Functional Partners:
SRF
Serum response factor.
    
 0.909
NKX2-5
NK2 homeobox 5.
   
  
 0.639
CNN2
Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
   
  
 0.607
MEF2C
Myocyte enhancer factor 2C.
   
  
 0.561
MAP2K4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
   
 0.556
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.530
TAGLN
Transgelin; Belongs to the calponin family.
      
 0.523
HAND2
Heart and neural crest derivatives expressed 2.
   
  
 0.515
SMYD1
SET and MYND domain containing 1.
   
 
 0.497
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
   
 0.495
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.