STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2UUbiquitin conjugating enzyme E2 U. (228 aa)    
Predicted Functional Partners:
UBE2V1
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.989
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 0.885
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.828
TRIP12
Thyroid hormone receptor interactor 12.
   
 0.783
RNF40
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
 0.767
RNF20
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
 0.767
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.760
UBA6
Ubiquitin like modifier activating enzyme 6.
   
 0.727
UBA7
Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
   
 0.727
UBA1
Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 0.727
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.