STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (829 aa)    
Predicted Functional Partners:
NR1D1
Nuclear receptor subfamily 1 group D member 1.
     
 0.594
THOC2
THO complex 2.
      
 0.574
BCL2L14
BCL2 like 14.
   
  
 0.560
HOMER3
WH1 domain-containing protein.
   
  
 0.529
PTGS1
Prostaglandin-endoperoxide synthase 1.
   
  
 0.528
G3UCL2_LOXAF
UPAR/Ly6 domain-containing protein.
     
 0.495
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
   
 0.492
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.492
RXFP2
Relaxin family peptide receptor 2.
   
 0.492
RXFP1
Relaxin family peptide receptor 1.
   
 0.492
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.