STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRD5A1S5A_REDUCTASE domain-containing protein. (135 aa)    
Predicted Functional Partners:
CYP17A1
Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.
     
 0.955
HSD17B3
Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.943
HSD17B2
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.936
HSD3B2
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
     
 0.928
CYP19A1
Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.
     
 0.928
LOC100654178
Uncharacterized protein; Belongs to the cytochrome P450 family.
     
 0.918
CYP21A2
Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family.
     
 0.917
G3T450_LOXAF
Aldo_ket_red domain-containing protein.
   
 
 0.915
AKR1D1
Aldo-keto reductase family 1 member D1.
   
 
 0.915
G3U442_LOXAF
Aldo_ket_red domain-containing protein.
   
 
 0.915
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.