STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN18Protein tyrosine phosphatase non-receptor type 18. (455 aa)    
Predicted Functional Partners:
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
 
 0.652
CSK
Tyrosine-protein kinase.
   
 0.644
MATK
Tyrosine-protein kinase.
   
 0.644
FRMPD2
FERM and PDZ domain containing 2.
 
 
  0.611
G3UI21_LOXAF
MAM domain-containing protein.
 
 
 
 0.580
SHC1
SHC adaptor protein 1.
   
 0.559
SHC3
SHC adaptor protein 3.
   
 0.559
ARHGEF4
Rho guanine nucleotide exchange factor 4.
      
 0.527
EGFR
Receptor protein-tyrosine kinase.
    
 0.485
BLK
Tyrosine-protein kinase.
   
 0.478
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.