STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DENND2ADENN domain containing 2A. (1000 aa)    
Predicted Functional Partners:
SUOX
Sulfite oxidase.
      
 0.664
IFT27
Intraflagellar transport 27.
    
 0.662
RAB35
RAB35, member RAS oncogene family.
    
 0.662
RHOBTB3
Rho related BTB domain containing 3.
      
 0.588
RAB9B
RAB9B, member RAS oncogene family.
     
 0.471
RAB9A
RAB9A, member RAS oncogene family.
     
 0.471
AVL9
AVL9 cell migration associated.
      
 0.469
ITSN2
Intersectin 2.
    
 
 0.412
G3U095_LOXAF
Uncharacterized protein.
    
 
 0.412
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
   
 
  0.409
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.