STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)    
Predicted Functional Partners:
LLGL1
LLGL scribble cell polarity complex component 1.
   
 0.940
LLGL2
LLGL scribble cell polarity complex component 2.
   
 0.940
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
 0.923
MAPK12
Mitogen-activated protein kinase.
    
 0.922
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 0.913
MAPK14
Mitogen-activated protein kinase.
    
 0.908
MAPK13
Mitogen-activated protein kinase.
    
 0.908
G3UJQ4_LOXAF
Uncharacterized protein.
  
  
 
0.900
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
0.759
GRIN1
ANF_receptor domain-containing protein.
   
 0.728
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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